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The drugs, which also include Mounjaro and Zepbound (tirzepatide), as well as Victoza and Trulicity, all belong to a class of medications known as glucagon-like peptide 1 (GLP-1) receptor agonists

When looking beyond the numbers on the scale, both drugs show incredible secondary health benefits, but Retatrutide holds a striking advantage in one particular area: Non-Alcoholic Fatty Liver Disease (NAFLD / MASH)

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Abbreviations A: Amyloid AD: Alzheimers disease BBB: Bloodbrain barrier CSF: Cerebrospinal fluid CV: Cardiovascular FDA: US Food and Drug Administration GLP-1: Glucagon-like peptide-1 GLP-1RA: Glucagon-like peptide-1 receptor agonist hs-CRP: High-sensitivity C-reactive protein MACE: Major adverse cardiovascular event MCI: Mild cognitive impairment OD: Once daily OW: Once weekly p-tau: Phosphorylated tau s.c.: subcutaneous T2D: Type 2 diabetes References Scheltens P, De Strooper B, Kivipelto M, Holstege H, Chtelat G, Teunissen CE, et al