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Individual variation is high and depends on your baseline metabolism, starting weight, and genetic factors

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Because semaglutide stays in your system for so long, a once-weekly injection ensures that there is always a consistent level of the medication working in your background

However, for individual health evaluations, excess adiposity should be assessed using direct body fat measurements or additional anthropometric criteria, and tissue or organ dysfunction should be assessed using laboratory measurements, or significant limitations in daily activities due to obesity