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Description
If side effects are significant at a new dose, staying at the current level for an additional four weeks or longer before attempting to increase again is the right approach

It plots concentration curves based on real pharmacokinetic data, showing peaks after injection, troughs before your next dose, and that gradual accumulation pattern that makes week five feel completely different from week one
10.1161/circulationaha.107.739938 139

Pinch about an inch of skin and fat
