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However, because of their lesser magnitude of glucose lowering, they are prescribed more commonly as an addition to another type of medicine rather than as monotherapy: Metformin: First-line therapy that decreases hepatic glucose output

In clinical trials, serious adverse effects requiring discontinuation were reported in less than 2% (,,)

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The researchers aimed to investigate whether specific medications for diabetes and obesity (namely, GLP-1 receptor agonists, SGLT2 inhibitors, and DPP4 inhibitors) had an impact on their likelihood of experiencing pancreatitis again