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Because the Phase 2 trial used a dose-escalation protocol starting participants at a lower dose before gradually increasing the weight loss observed at one month reflects early-stage, titration-phase treatment rather than the drug's full therapeutic effect

CsCl and CsOH were from Alfa Aesar (Avocado Research Chemicals, Heysham, UK)

2016 GLP-1 , 13%, 22%

MariTide stands alone as the only therapy in late-stage development to offer the paradigm-changing prospect of strong efficacy and favorable tolerability at monthly, every other month or even every quarter dosing, Amgen CEO Robert Bradway said during the pharmas full year 2025 earnings call Tuesday afternoon