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Moreover, it was also shown that while heat acclimation reduced the response of the brown adipocytes to glucagon, cold acclimation did not modify it [27]
When the TLR receptor binds to its ligand, it activates downstream signaling pathways that trigger the production of a variety of signaling molecules and cytokines, which ultimately leads to an inflammatory response and the activation of immune cells
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Shimizu, I., Hirota, M., Ohboshi, C
