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Our group reported that enhanced beta-cell GLP-1R signaling activates alpha-cell PC1/3 expression and GLP-1 production, which is associated with improved glucose tolerance and GSIS following VSG in mice (39) ( Figure 4 )
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It is commonly used for type 2 diabetes and obesity, but some people with polycystic ovary syndrome (PCOS) or ovarian cysts may also take it
