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In summary, exenatide was a trailblazer
Many patients who start with oral semaglutide due to insurance coverage eventually switch to compounded injectables when results disappoint
Among the 3,532 participants in the FLOW trial, 19.2% (678 individuals) had heart failure at baseline, with 47.9% classified as having HFpEF, 18.1% as having heart failure with reduced ejection fraction (HFrEF), and 33.9% with unknown status
The direct and weight-independent actions of some new obesity pharmacotherapies in ectopic fat of specific organs may further enhance the potential for tailored treatment choices based on patients complications
