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Elevated plasma fatty acid levels, being associated with an increased risk of HF, can give rise to lipotoxicity (81)
Drucker DJ, Buse JB, Taylor K, et al
The cAMP/PKA pathway inhibits voltage-gated potassium channels that respond to depolarization, opens and allows K + efflux, repolarizing the cell and allowing increased calcium influx through voltage-dependent calcium channels, resulting in the exocytosis of insulin from -cells (115)
On GLP-1 medications where you might already struggle with reduced fluid intake , this is especially important to remember
