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Charney AW, Ruderfer DM, Stahl EA, Moran JL, Chambert K, Belliveau RA, et al

"OKV-119 is designed to mimic many of the physiological effects of fasting improved insulin sensitivity, reduced fat mass and more efficient energy metabolism without requiring significant changes in feeding routines or disruption of the human-animal bond that often centers around food." The MEOW-1 study aims to evaluate the safety, tolerability and efficacy of the weight-loss medication in overweight or obese cats

This will allow for the stratification of results based on the presence of pathological changes and permit the evaluation of an interventions effect on the risk of developing symptoms