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What the Research Shows on Weight Loss Clinical trials of bupropion-naltrexone (Contrave) have shown average weight loss of around 5 percent of body weight over one year in patients who also follow a reduced-calorie diet and exercise program

J Clin Endocrinol Metab (2003) 88:271925

Meoni S, Macerollo A, Moro E 2020

Extracting the fluid from a Wegovy pen can introduce bacteria and other contaminants into the medicine, increasing the likelihood of infection
