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Bloom, Glucagon-like peptide-1 7-36: a physiological incretin in man

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Clinical studies indicate that stopping GLP-1 therapy abruptly can lead to weight regain due to hormonal and metabolic adaptations

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Monitoring requirements Both compounds require medical monitoring, but the specifics differ

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Originally approved by the FDA in 2017 as a weekly injection to lower blood sugar under the name Ozempic, semaglutide was later approved in 2019 as a tablet form called Rybelsus to treat diabetes

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