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Patients with a personal or family history of medullary thyroid carcinoma or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) should not take these medications

In a 2-year CV outcomes trial with semaglutide injection involving patients with type 2 diabetes mellitus and high CV risk, diabetic retinopathy complications (which was a 4-component adjudicated endpoint) occurred in patients treated with semaglutide injection (3%) compared to placebo (1.8%)

And for those comparing across the triple agonist space, mazdutide versus retatrutide and Ozempic versus retatrutide provide helpful context

Lower back pain: A condition that may improve after body lift surgery due to better posture and reduced excess skin