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[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Giel K.E., Rieber N., Enck P., Friederich H.C., Meile T., Zipfel S., Teufel M
Notably, PTX and YM-25890 treatment had no effect on 15 mM KCl-stimulated calcium mobilization (Figure 2D), suggesting that the inhibitory effects observed on hGPR17L-mediated calcium signaling are not due to toxicity or non-specific effects on calcium signaling

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Some people experience mild oral irritation from holding the drops under the tongue for the recommended absorption period
