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Additionally, lixisenatide was associated with fewer gastrointestinal symptoms compared to exenatide, while long-acting GLP-1RAs generally caused less nausea and vomiting but more diarrhea than short-acting agents (49)

Gorbea E, Kidwai S, Rosenberg J

CBC also noted that Canada is the only country where Novo Nordisk allowed the patent for its semaglutide drugs to expire, with regulatory exclusivity ending January 4 [Source: cbc.ca/news/health/ozempic-glp1-health-canada-generic-9.7034498]
What matters now is how systems, insurers, and practices adapt, not just whether the drugs work