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Some patients may also experience changes in blood glucose regulation that could affect temperature perception

Here's the "Bridge to Anticoagulation" approach: Step 1: HOLD and TRANSFUSE Stop therapeutic anticoagulation Give platelet transfusions (unlike TTP, this is safe in CAPS) Continue immunosuppression and plasma exchange Step 2: Watch the Safety Window Platelets 50k: Resume therapeutic anticoagulation Step 3: Choose UFH Short half-life, reversible with protamine Avoid LMWH and warfarin initially Rule out HIT if platelet recovery stalls Fourth line: Eculizumab If platelets stay below 20k despite triple therapy, think complement-mediated microangiopathy

[1] Injectable GLP-1 agonists are divided into short-acting and long-acting formulations

doi: 10.1016/j.clinthera.2007.11.006