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Research indicates that GLP-1 signaling may also affect brain regions associated with dopamine-mediated reward pathways , which play a central role in reinforcement and craving

During the active weight loss phase, particularly with rapid weight reduction, hormonal fluctuations may temporarily affect menstrual regularity and ovulation patterns
As AOMs are prescribed across a range of ages, metabolic profiles, and comorbid conditions, clinicians must consider tolerability, contraindications, and the potential for drugdrug interactions

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