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Most patients see their symptoms go away within 8 days after they start [2]

Monitoring thyroid function through TSH and free T3 testing helps identify whether thyroid supplementation might benefit users experiencing persistent fatigue or metabolic slowdown despite appropriate tirzepatide dosing

Further, the CVOTs in general also suggested a potential benefit of GLP-1 RAs on HF, positioning GLP-1 RAs as another advanced option alongside SGLT2 inhibitors in the otherwise sparse treatment armamentarium for especially HFpEF

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