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Average Weight Loss After ~1 Year Key research findings: Semaglutide 2.4 mg : ~15% weight loss over 68 weeks

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Overview of the Phase 2 NEJM Trial Design and Participants The phase 2 trial was a randomised, double-blind, placebo-controlled, dose-ranging study enrolling 338 adults with obesity or overweight without type 2 diabetes, assessing retatrutide doses of 1 mg, 4 mg, 8 mg, and 12 mg over 48 weeks

By acting on both, Tirzepatide can potentially lead to even greater reductions in body weight and blood sugar, as shown in recent clinical trials
