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Prevalence of comorbid substance use in major depressive disorder in community and clinical settings, 19902019: systematic review and meta-analysis
This demonstrated the antagonistic effect while also providing evidence for the crucial role of GIP receptor signaling in potentiating the insulin response to oral glucose (61)

Available from: [Google Scholar] 50.Finan B, Ma T, Ottaway N, Muller TD, Habegger KM, Heppner KM, et al
The vascular hypometabolism hypothesis reframes dementia as a disorder of energy delivery, where chronic reductions in cerebral blood flow and glucose utilization precede and likely contribute to amyloid and tau pathology