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There needs to be caution when interpreting these reports because confounders such as weight gain may have influenced the development of increased ICP
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The ability of GLP-1 RAs to penetrate the bloodbrain barrier and mediate central effects (e.g., appetite suppression) can differ based on the molecular structure of the agonist and individual patient characteristics such as bloodbrain barrier permeability, obesity, and metabolic health

N., Wharton, S., Connery, L., Alves, B., Saucier, J
