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However, the recovery of these regenerative capabilities (by increased expression of NAMPT for example) change the physiology of the cells towards stem-like cells, gaining some cancer properties, such as unlimited proliferative capacity, altered metabolism, DNA-repair, methylation alterations, with phenotype similar to CSCs, which deregulation by any other mutation initiate the tumor
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Lokhnygina, J.B
The diabetes group was divided into two subgroups based on HbA1C, with a cutoff value of 7.5%.The MRI indices of glymphatic function were compared with cortical thickness and cognitive dysfunction
