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This increase in cAMP activates downstream effectors such as protein kinase A (PKA) and exchange protein directly activated by cAMP 2 (Epac2), which modulate various cellular responses [8]

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Funding This work was supported by: open access funding provided by the: National Plan for NRRP Complementary Investments (PNC, established with the decree-law 6 May 2021, n

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