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doi: 10.1111/j.1365-2125.2009.03371.x

13 Naloxone challenge: a trial dose of 0.4 mg IV should be given, and the patient observed for signs of withdrawal

Whether you have surgery to remove a tumor, usually from the adrenal, that makes excess cortisol, or whether you take any drug that interferes with cortisol action, you have something called glucocorticoid withdrawal syndrome or cortisol withdrawal syndrome
