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For patients requiring additional glycaemic control, the dose may be increased to the maximum licensed dose of 2 mg once weekly after at least four weeks at the 1 mg dose, as per the UK SmPC

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7ac, Supplementary Tables 7 and 8) and led to greater relative engagement of this peptide with TMs 5, 6 and 7, relative to rAmy, which interacted more with ECL2 (Supplementary Fig

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