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Moreover, adipose tissue macrophages in obesity adopt a pro-inflammatory M1 phenotype, further amplifying systemic immune activation, whereas weight reduction favors a switch toward an anti-inflammatory M2 phenotype [39]

Phentermine Phentermine, a sympathomimetic amine that suppresses appetite, was approved by the FDA in 1959 for short-term use (12 weeks) in adolescents over 16 years [75,88]

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Over time, exposure to untreated hyperthyroidism could harm cognition, generating brain fog or memory deficiencies