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Evidence: The SCALE clinical programme demonstrated significant benefits, with participants achieving an average weight loss of approximately 8 per cent of baseline body weight at 56 weeks, compared with around 3 per cent in those who received lifestyle intervention alone

Do not stop your semaglutide without consulting your provider, since abrupt discontinuation can cause blood sugar fluctuations and rebound appetite

For patients who cannot tolerate higher-potency GLP-1 therapies or who prefer a longer-established safety profile, Saxenda may be a reasonable option

That is a clinically meaningful difference, and it has influenced how doctors view the two options for their patients