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Specifically, treatment with exenatide acetate increased the ratio of p -AMPKThr172/AMPK, inhibited NF-B p65 phosphorylation, and downregulated pro-inflammatory markers, including IL-1 and TNF- [69]
This dual mechanism produces different downstream effects on brain chemistry, appetite regulation, and potentially sexual function
Glucagon-like peptide one receptor agonists (GLP-1RA) can diminish neuroinflammation and oxidative stress and reduce AD models amyloid-beta deposition or tau hyperphosphorylation [57,58]
If nausea occurs, eating smaller, blander meals and sipping ginger tea often provides relief
