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In addition to the metabolic and phenotypic parameters reported in the present study, previous research has demonstrated that melanocortin-4 receptor (MC4R) deficiency is associated with profound alterations in multiple hypothalamic neuropeptides and peripheral hormones involved in energy balance regulation

More recently, trials have explored the potential of semaglutide, a more potent cousin of liraglutide, to promote weight loss

Jorsal A, Kistorp C, Holmager P, Tougaard RS, Nielsen R, Hnselmann A, et al

Mol Metab 2019;20:5162 [DOI] [PMC free article] [PubMed] [Google Scholar] 27
