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Evidence from Human In Vitro and Clinical Studies on the Effect of GLP-1 RAs on Disease Activity in Non-IBD Immune-Mediated Inflammatory Diseases (IMIDs) Only three human (one in PsO and two in rheumatoid arthritis (RA)) in vitro studies met the eligibility criteria for inclusion as basic science evidence that GLP-1RAs have therapeutic anti-inflammatory potential for treating non-IBD IMIDs (Table 2)

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Significant weight loss was achieved 12 months after the initiation of pharmacotherapy and the weight loss was higher in the semaglutide group than in the liraglutide group [47]
