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This results in coordinated metabolic improvements via tissue-specific activation of signalling pathways that improve glucose homeostasis, decrease inflammation, and help to improve overall cardiovascular and metabolic health

Those trials will see a total of 3,700 people with early stage Alzheimers given semaglutide or a placebo for up to 3.3 years to test if the med has a positive impact on cognitive decline

Critics, however, argue the conclusion is premature

The three mechanisms are: (1) slowed gastric emptying paired with a bile acid surge, (2) direct GIP/GLP-1 receptor activation in the intestine itself, and (3) a rebalancing gut microbiome