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The best choice depends on the persons health history, treatment goals, eligibility, and tolerance

Interestingly, during these trials, individuals who received a placebo (an injection without medication) reported more serious side effects compared to those who received semaglutide

Later in 2025, NPR reported that the popularity of GLP-1s has also led to counterfeit products making their way onto the mass market, prompting the Food and Drug Administration (FDA) to issue a warning about counterfeit Ozempic to the public

That triple agonism is why researchers across the globe have turned their attention, and their budgets, toward this specific compound