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The keto diet, especially during the initial adaptation phase (often called "keto flu"), can also cause nausea, fatigue, headaches, and digestive changes
Naltrexone/bupropion has been evaluated in several studies and has shown greater weight loss compared to placebo when combined with a diet and exercise program
Gallbladder complications, including gallstones and cholecystitis, occur at slightly higher rates in patients using GLP-1 receptor agonists, likely related to rapid weight loss rather than direct drug effects
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