semaglutide oasis 4 In the phase 3 trial, once-daily oral at a dose of 25 mg resulted in a greater mean reduction in body weight than placebo in participants with overweight or oasis-4 semaglutide oasis 4 trial

Many patients starting semaglutide wonder if a low dose will 'work' right away

Thats when side effects often appear, such as: Nausea or bloating Dizziness Headaches Constipation Fatigue or low energy Dry mouth and signs of dehydration These symptoms are typically not harmful, but they can interrupt daily routines, especially when combined with lifestyle changes such as a new diet or exercise plan

Semaglutide and related weight-loss medications, known as GLP-1 agonists, may slow biological ageing, reduce inflammation, improve cognitive function and gut health, and reduce alcohol use in people living with HIV, according to studies presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2025)

Results vary based on your starting weight and adherence to injections