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Changes from baseline in cardiovascular, metabolic, and inflammatory biomarkers among GLP-1 drug users were as follows: Triglycerides: -16.4 mg/dL LDL cholesterol: -7.3 mg/dL HbA1c: -0.3 percentage points CRP: -0.6 mg/dL ESR: -3.0 mm/hr These were all numerically greater than corresponding changes for non-users, but often the differences didn't reach statistical significance

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Del Prato 2021 Multicenter RCT (SURPASS-4) GI events during titration

However, the authors were unable to assess the incidence of FG or whether SGLT2 inhibitors were causative