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Specifically, research shows that Akkermansia secretes a protein called P9 that stimulates the production of GLP-1 in the gut

These findings suggest that while bitter substances promise to improve glucose homeostasis, their potential adverse effects beyond the gastrointestinal system warrant careful consideration [196]

So in many ways, these compounding pharmacies filled in a really important void

Nature 415 , 871880 (2002) Moon, M
