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In animal models, GIP has been linked to improved energy expenditure, hinting that it may play a role in burning calories more efficiently

These findings highlight the central role of formulary and coverage decisions in shaping treatment access and underscore the importance of continued monitoring as the GLP-1 therapeutic landscape evolves

[16] [19] Subsequent analysis of SUSTAIN-6 data revealed that the increased risk was concentrated among patients who entered the trial with pre-existing diabetic retinopathy and experienced rapid improvements in glycemic control

Cardiovascular benefits, including reduced risk of heart disease and stroke, continued to accrue over the study period