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The subjects who took Zepbound had more weight loss than those who were given a placebo, and having the other conditions did not make a difference in that weight loss

The characteristics of the first two subgroups are related in part to a more prolonged duration of disease and so their diminished responses are in line with general experience surrounding the relative efficacy of glucose-lowering agents and the extent and duration of preexisting T2D

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Nausea typically develops when doses increase too rapidly or when the medication first reaches its peak concentration in your bloodstream