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La molcula se construye sobre un esqueleto modificado del GIP nativo, al que se incorporan sustituciones de aminocidos no cannicos (aminoisobutrico, Aib) en posiciones 2 y 13 para conferir resistencia enzimtica frente a la dipeptidil-peptidasa-4 (DPP-4), y una cadena de cido graso C20 di-cido conjugada va un linker Glu-2xOEG en el residuo Lys20

Reduced inflammation : Chronic inflammation is linked to numerous health issues, including heart disease and diabetes

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While tirzepatide works by activating the GLP-1 and GIP receptors, retatrutide activates GLP-1, GIP, and GCG receptors, which may offer even more benefits