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Indeed, dual GLP-1 ligands that activate the GLP-1R but simultaneously block the GIPR (AMG133 or maridebart cafraglutide, MariTide ) are currently in clinical trials for obesity/weight loss and seem to work as well as (if not even better than) dual GLP-1R/GIPR agonists, such as tirzepatide (Zepbound ) (see below) [52]
Hanbang Technology has been deeply involved in the field of preparative liquid chromatography for more than 20 years, has rich experience in peptide purification, and has a mature GLP-1 high-pressure chromatography purification process

When used alongside a healthy diet and regular exercise, both medications can support weight loss and help maintain a healthy weight over time
