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For patients, payers, and health systems, the triple-agonist era does not eliminate bariatric surgery - it creates a new category of patients who can access surgical-equivalent weight loss without surgical risk, provided they remain on drug and access it at a price their payer will cover

Weight loss without exercise is possible through diet alone, but combining dietary changes with regular physical activity improves outcomes across every metric, from fat loss to muscle preservation to metabolic health

Research shows that staying on a peptide continuously, without a break, may make it less effective over time

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