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Furthermore, blockade of BTRs (e.g., by probenecid), or the downstream pathways relating to BTR signaling, including inositol 1,4,5-trisphophate, phospholipase C 2 , protein kinase C and/or phosphodiesterase, attenuates GLP-1 secretion induced by bitter tastants (21, 58, 59)

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In 2020 Boris Johnson launched the governments anti-obesity strategy, which included plans for a ban on TV and online adverts for food high in fat, sugar and salt before 9pm and ending deals such as buy-one-get-one-free on unhealthy food high in salt, sugar and fat.

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