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The role of central GIP receptors remains less well characterized and is an area of ongoing investigation

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Sarcoplasmic/endoplasmic reticulum Ca2 + -ATPase 2a (SERCA2a), a pivotal protein in the excitationcontraction coupling process, maintains calcium homeostasis in cardiomyocytes by transporting Ca2+ from the cytoplasm back into the sarcoplasmic reticulum