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Developed by Innovent Biologics, it rivals Western treatments like Ozempic while enhancing affordability amid Chinas soaring diabetes burden
Here authors report the cryo-EM structure of GLP-1R bound to an ago-allosteric modulator in complex with heterotrimeric Gs which offers insights into the molecular details of ago-allosterism.

GLP-1 medications, also known as glucagon-like peptide-1 receptor agonists, are a powerful tool for managing type 2 diabetes

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