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In a clinical trial participants lost an average of 15% of their body weight after 68 weeks

Many people start with the moderate ~500 calorie deficit

Tirzepatide itself is not typically listed among contraindicated medications, but the reason you take it matters

Interestingly, female participants lost more weight than male participants over the 48 weeks, achieving 28.5% and 21.9% with 12 mg, respectively
