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The most common side effects include nausea, constipation, bloating, and heartburn

This suggests that different genetic mechanisms at the tissue level may be involved in pubertal development in individuals with PWS (213, 214)

Studies have shown that GLP-1 agonists can trigger effects in the brain, the heart, the liver, the pancreas, the stomach, and the musclesmeaning that they could have implications for conditions other than type 2 diabetes and obesity, such as heart disease, kidney disease, liver disease, and even neurological conditions such as Alzheimer's disease

2) with or without obesity (79), acromegaly (80), before and after gastric bypass surgeries (79), and in totally pancreatectomized patients (81)