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While those with obesity stand to reap considerable health benefits from fat loss, the potential benefits of fat loss among healthy-weight individuals are minimal and are unlikely to offset the sizable health risks associated with reduced lean mass

Peer review Peer review information Nature Medicine thanks Andrew Feigin, Tanya Gurevich and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Danish multinational pharmaceutical company Novo Nordisk recently announced that the United States Food and Drug Administration (FDA) approved the companys injectable weight-loss drug Wegovy for reducing risks of adverse heart disease-related events

Effect of Roux-en-Y gastric bypass surgery on diabetes remission and complications in individuals with type 2 diabetes: A Danish population-based matched cohort study