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Patients who lost less than 20 pounds on GLP-1 medications and were subsequently prescribed phentermine experienced greater weight loss while on phentermine in the year following GLP-1 treatment than patients who lost at least 20 pounds on the GLP-1 medication.

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The respective reductions in body mass index (BMI) and waist circumference were -1.7 kg/m2 (95% CI, -2.4 to -1.0 kg/m2
