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In particular, GLP1-RA counteract the action of angiotensin II (ANG II) inhibiting its synthesis, increasing the inactivation of its circulating form and contrasting its action on target tissue like glomerular endothelial cells and cardiomyocytes

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Conversely, we observed that primary and metastatic tissue in the GLP-1R-low group shared several immune-related genes ( Supplementary Figure 3b
