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Clinical Recommendations and Provider Decision Framework Major organizations including the American Academy of Pediatrics, American College of Obstetricians and Gynecologists, and lactation research groups recommend against GLP-1 use during breastfeeding

GIP also supported de novo lipogenesis from glucose as well as lipolysis (the mobilisation of FFA in the fasting state)

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Degraded peptide means reduced potency, which means a slower, less predictable response timeline